Simparica® Chewables for dogs

Ticks and fleas don’t slow down at the end of the month. Your dog’s tick and flea protection shouldn’t either. Simparica starts—and stays—strong all month long¹. Approved for dogs 6+ months old, weighing more than 2.8 lbs., Simparica is a tasty, pork liver-flavored monthly chewable that protects dogs from ticks and fleas for 35 days¹. It is approved to kill 6 types of ticks including the Gulf Coast tick, Brown dog tick, Deer tick, American dog tick, Lone Star tick, and Asian longhorned tick. It’s FDA-approved to block infections that may cause Lyme disease, by killing deer ticks. Treatment may begin at any time of the year and should continue monthly, year-round without interruption. Feed one chewable; administer at monthly intervals. Simparica comes with a 100% satisfaction guarantee on prevention. If you feel that Simparica isn’t providing sufficient protection, please call Zoetis’ medical support team to discuss the satisfaction guarantee at 1-888-ZOETIS1. Enrolling in auto ship provides savings, convenience, and the peace of mind that your dog never misses a dose. Simparica is eligible for Zoetis Petcare Rewards Program. Sign up for free to earn points on every dollar spent on eligible purchases that can be redeemed for services at your vet. Learn more by visiting ZoetisPetcare.com/Rewards.

Simparica is for use only in dogs 6 months of age and older. Simparica, which contains sarolaner, a member of the isoxazoline class, may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding, or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaPI.com.

1. Six RH, Everett WR, Young DR, et al. Efficacy of a novel oral formulation of sarolaner (Simparica®) against five common tick species infesting dogs in the United States. Vet Parasitol. 2016;222:28-32.

2. Six RH, Geurden T, Carter L, et al. Evaluation of the speed of kill of sarolaner (Simparica®) against induced infestations of three species of ticks (Amblyomma maculatum, Ixodes scapularis, Ixodes ricinus) on dogs. Vet Parasitol. 2016;222:37-42.

Dogs (6 months of age and older)

Sarolaner

Parasite preventative, Chewable tablet

Simparica Chewable tablets are pork liver flavored.*

Body Weight	Sarolaner (per tablet)
2.8 to 5.5 lbs	5 mg
5.6 to 11 lbs	10 mg
11.1 to 22 lbs	20 mg
22.1 to 44 lbs	40 mg
44.1 to 88 lbs	80 mg
88.1 to 132 lbs	120 mg
>132 lbs	Administer the appropriate combination of tablets to cover the dog’s full body weight.

Please ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above.

Simparica Chewables should be administered as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.

If a dose is missed, administer Simparica immediately to resume monthly dosing and notify your veterinarian. Do not give two doses at once.

If multiple doses have been missed, consult your veterinarian prior to restarting the monthly dosing schedule. If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian.

Simparica is given once a month, with or without food, as directed by your veterinarian.

Store in a cool, dry place at a controlled room temperature (at or below 86°F), with excursions permitted up to 104°F. Keep this and all other medications in a secure location out of the reach of children and animals. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing.

Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store this medication properly (e.g., away from the bathroom, kitchen sink, or other damp places).

The most common side effects of this medication are vomiting and diarrhea.

Contact your veterinarian immediately if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).

The information provided above may not encompass all possible side effects. Please notify your veterinarian if your pet experiences any side effects, including those listed above, or if you notice anything unusual.

For oral use in dogs only. Do not use Simparica in cats.

Not for use in humans. Keep this and all medications out of reach of children and animals to prevent accidental ingestion or overdose.

Use with caution in dogs with a history of seizures or neurologic disorders.

Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to it or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

While there are no documented drug or food interactions reported for Simparica Chewables, potential interactions may still be possible. As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.

Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Zoetis at 1-888-963-8471 or Vetsource Pet Owner Care at 877-738-4443.

If you have any reason to suspect accidental consumption or overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline also provides a 24/7 animal poison control service at 855-764-7661.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

For additional information about this product and how it fits into your pet's individual treatment plan, please consult your veterinarian.