NexGard Flea and Tick Chewable for Dogs
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Vet-recommended flea and tick control that kills fleas fast, before they can lay eggs.
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This flea and tick treatment product is FDA-approved to prevent Lyme infections as a direct result of killing black-legged ticks.
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Kills fleas and ticks all month long.
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NexGard (afoxolaner) flea and tick chewables are #1 dog-preferred and have a delicious beef flavor.
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Safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more
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Administered orally with or without food and remains effective for a full month.
With one little NexGard (afoxolaner) chew comes the confidence that you’re giving your dog vet-recommended flea and tick control1. NexGard flea and tick control chewable is approved by the FDA to prevent infections that cause Lyme disease in dogs as a result of killing black-legged ticks. And each bite-sized monthly flea and tick treatment dose is safe to give to puppies and dogs as young as 8 weeks, weighing as little as 4 pounds. NexGard chews are #1 dog preferred and have a delicious beef flavor. And because you should feel just as good about the medicine your dog receives as he does taking it, the ingredients in each NexGard flea and tick protection chew have been carefully designed to quickly kill fleas and ticks for a full month, killing fleas before they have a chance to lay eggs and black-legged ticks before they transmit Lyme infections. NexGard chews are flea and tick control for dogs that are easy to give, effective, and enjoyable, month after month.
Emergency Use Authorization for NexGard (afoxolaner) for New World screwworm (NWS)
The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) for the emergency use of the approved product NexGard (afoxolaner) for the treatment and prevention of infestations caused by NWS (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies. NexGard is not approved or conditionally approved for this use.
NexGard is approved for other uses.
Limitations of Authorized Use
NexGard (afoxolaner) is authorized only for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of NexGard (afoxolaner) under section 564(b)(1) of the Federal Food, Drug, and Cosmetic Act (FD&C Act) 21 U.S.C. § 360bbb-3(b)(1), unless the declaration is terminated or the authorization is revoked sooner.
IMPORTANT SAFETY INFORMATION:
NexGard (afoxolaner) is for use in dogs only. The most frequently reported adverse reactions include vomiting, pruritus (itching), lethargy, diarrhea, and lack of appetite. The safe use of NexGard chews in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders.
References:
1. Data on file at Boehringer Ingelheim.
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs
Drug class
Isoxazoline ectoparasiticide
Ingredients
Active ingredient(s): Afoxolaner
Product flavoring
NexGard Chewables are beef flavored.*
*Contains soy; according to the manufacturer, NexGard is gluten-free and does not contain actual beef.
Product strength & size
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Breed Size
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Weight Range
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Afoxolaner (per chewable)
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Small
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4 – 8 lbs.
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11.3 mg
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Medium
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10.1 – 24 lbs.
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28.3 mg
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Large
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24.1 – 60 lbs.
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68 mg
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Extra Large
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60.1 – 121 lbs.
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136 mg
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Over 121 lbs.
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Administer the appropriate combination
of chewables to cover the dog’s full
body weight.
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Please ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above.
Usage
NexGard should be administered as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian.
Manufacturer Dosage and Administration*
NexGard (afoxolaner) is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). NexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule.
Flea Treatment and Prevention: Treatment with NexGard may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.
Tick Treatment and Control: Treatment with NexGard may begin at any time of the year.
*Additional information may be provided within the manufacturer’s full Prescribing Information. Always follow the specific instructions provided by your veterinarian regarding your pet's care.
Storage
Store in a cool, dry place at a controlled temperature at or below 86°F with excursions permitted up to 104°F. Keep this and all other medications in a secure location out of the reach of children and animals. Tablets should remain sealed in their original packaging and should only be taken out at the time of dosing.
Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store this medication properly (e.g., away from the bathroom, kitchen sink, or other damp places), as outlined on the product label.
Side effects
The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite.
Contact your veterinarian immediately if your pet experiences severe or persistent vomiting, complete loss of appetite, tremors, difficulty walking, decreased coordination, or seizures.
The information provided above may not encompass all possible side effects. Please notify your veterinarian if your pet experiences any side effects, including those listed above, or if you notice anything unusual.
Precautions
Before using this product, please review the manufacturer’s full Prescribing Information for any relevant warnings and safety precautions.
For oral use in dogs only.
Not for use in humans. Keep this and all other medications out of reach of children and animals. In case of accidental ingestion, contact a physician immediately.
Afoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.
The safe use of NexGard (afoxolaner) in breeding, pregnant or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian prior to use if your pet falls into one of these categories.
Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to it or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Food and drug interactions
While there are no specific food or drug interactions reported for this product, potential interactions may still be possible. Please consult your veterinarian if you have any questions or concerns prior to use. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.
Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Boehringer Ingelheim Animal Health at 1-888-637-4251 or Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect accidental ingestion or overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: The contact information provided above is for third-party services in the event of a potential poison-related emergency. Consultation fees may apply for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
For additional information about this product and how it fits into your pet's individual treatment plan, please consult your veterinarian.
Last revised: 7/30/2026